Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 6/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.51 |
| ▸ | PPARG | P37231 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 3/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344629 | 0.87 | MMP12 (0.55) | ALOX5PPARGGRIK1PPARAMMP3 | |
| SCHEMBL8505435 | 0.87 | PTGES (0.48) | PTGESALOX5PPARGRARBGRIK1 | |
| SCHEMBL6412929 | 0.82 | RARB (0.53) | PTGESALOX5PPARGRARBPPARA | |
| SCHEMBL7377067 | 0.82 | RARB (0.53) | PTGESALOX5PPARGRARBPPARA | |
| SCHEMBL7372219 | 0.82 | RARB (0.53) | PTGESALOX5PPARGRARBPPARA | |
| SCHEMBL6416023 | 0.81 | RARB (0.55) | PTGESALOX5PPARGLMNARARB | |
| SCHEMBL8505233 | 0.80 | GRIK1 (0.54) | PPARGGRIK1PPARAMMP3MMP2 | |
| SCHEMBL7343532 | 0.80 | GRIK1 (0.54) | PPARGGRIK1PPARAMMP3MMP2 | |
| SCHEMBL8041180 | 0.80 | PPARG (0.61) | PTGESALOX5PPARGGRIK1PPARA | |
| SCHEMBL8690347 | 0.78 | PPARG (0.49) | PTGESALOX5PPARGLMNARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937036-B1 | SUBSTITUTED 4-BIPHENYL-4-HYDROXYBUTYRIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITORS | BAYER AG (US) | 2001-12-05 | — | — | EP | claimed |
| EP-0937036-A1 | SUBSTITUTED 4-BIPHENYL-4-HYDROXYBUTYRIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITORS | Bayer Corporation (US) | 1999-08-25 | — | — | EP | claimed |
| US-5939583-A | ANTIARTHRITIC AGENTS; BONE, CARDIOVASCULAR, BRAIN, NERVOUS SYSTEM DISORDERS; ANTITUMOR AND ANTIMETASTASIS AGENTS | BAYER CORPORATION (US) | 1999-08-17 | — | — | US | claimed |
| WO-1998022436-A1 | SUBSTITUTED 4-BIPHENYL-4-HYDROXYBUTYRIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITORS | BAYER CORPORATION (US) | 1998-05-28 | — | — | WO | claimed |
| EP-0937036-B1 | SUBSTITUTED 4-BIPHENYL-4-HYDROXYBUTYRIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITORS | BAYER AG (US) | 2001-12-05 | — | — | EP | disclosed |
| EP-0937036-A1 | SUBSTITUTED 4-BIPHENYL-4-HYDROXYBUTYRIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITORS | Bayer Corporation (US) | 1999-08-25 | — | — | EP | disclosed |
| US-5939583-A | ANTIARTHRITIC AGENTS; BONE, CARDIOVASCULAR, BRAIN, NERVOUS SYSTEM DISORDERS; ANTITUMOR AND ANTIMETASTASIS AGENTS | BAYER CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| WO-1998022436-A1 | SUBSTITUTED 4-BIPHENYL-4-HYDROXYBUTYRIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITORS | BAYER CORPORATION (US) | 1998-05-28 | — | — | WO | disclosed |