Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.49 |
| ▸ | PTGES | O14684 | 6/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | BRS3 | P32247 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690007 | 0.88 | MMP12 (0.50) | PPARGALOX5PPARAFFAR1 | |
| SCHEMBL6412929 | 0.87 | RARB (0.53) | PPARGPTGESALOX5PPARAMEN1 | |
| SCHEMBL7377067 | 0.87 | RARB (0.53) | PPARGPTGESALOX5PPARAMEN1 | |
| SCHEMBL7372219 | 0.87 | RARB (0.53) | PPARGPTGESALOX5PPARAMEN1 | |
| SCHEMBL6416023 | 0.86 | RARB (0.55) | PPARGPTGESALOX5PPARALMNA | |
| SCHEMBL8505435 | 0.81 | PTGES (0.48) | PPARGPTGESALOX5PTPN11PPARA | |
| SCHEMBL8688109 | 0.81 | PPARG (0.48) | PPARGPPARABRS3 | |
| SCHEMBL8041180 | 0.78 | PPARG (0.61) | PPARGPTGESALOX5PPARAMEN1 | |
| SCHEMBL7353605 | 0.78 | PTGES (0.51) | PPARGPTGESALOX5PPARALMNA | |
| SCHEMBL7985219 | 0.77 | LMNA (0.54) | PPARGPTGESALOX5PPARALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789434-A | ACID, ESTER OR AMIDE DERIVATIVES AS ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS AND REDUCTION OF CARTILAGE DETERIORATION | BAYER CORPORATION (US) | 1998-08-04 | — | — | US | disclosed |