Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354017 | 1.00 | ADRA1A (0.50) | ADRA1AADRA2ACYP2D6MAPK1MEN1 | |
| SCHEMBL6372113 | 0.84 | ADRA1A (0.54) | ADRA1AADRA2ACYP2D6MAPK1MEN1 | |
| SCHEMBL6372120 | 0.84 | ADRA1A (0.54) | ADRA1AADRA2ACYP2D6MAPK1MEN1 | |
| SCHEMBL6372116 | 0.84 | ADRA1A (0.54) | ADRA1AADRA2ACYP2D6MAPK1MEN1 | |
| SCHEMBL10665110 | 0.84 | ADRA1A (0.54) | ADRA1AADRA2ACYP2D6MAPK1MEN1 | |
| SCHEMBL490457 | 0.82 | ADRA1A (0.53) | ADRA1AADRA2ACYP2D6MAPK1MEN1 | |
| SCHEMBL8900397 | 0.79 | ADRA1A (0.53) | ADRA1AADRA2ACYP2D6MEN1KMT2A | |
| SCHEMBL6372898 | 0.79 | HTT (0.49) | ADRA1AADRA2ACYP2D6MAPK1MEN1 | |
| SCHEMBL27546834 | 0.78 | ADRA1A (0.54) | ADRA1AADRA2ACYP2D6MAPK1MEN1 | |
| SCHEMBL491226 | 0.77 | ALOX15 (0.48) | MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6337394-B2 | N-ACYL-HETEROCYCLE-CARBOXYAMIDES THAT ARE N-SUBSTITUTED WITH AMIDINO-SUBSTITUTED RINGS; COMPETITIVE INHIBITORS OF THROMBIN; ANTICOAGULANTS | ASTRAZENECA AB (SE) | 2002-01-08 | — | — | US | disclosed |
| US-20010046981-A1 | COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 2001-11-29 | — | — | US | disclosed |
| EP-1036061-A1 | NEW COMPOUNDS | AstraZeneca AB (SE) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999029664-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010046981-A1 | COMPOUNDS | F2, SERPINC1, SERPINB1 | ADRA1A 3104/4885ADRA2A 3907/4885CYP2D6 806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.