Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP14 | P54578 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | ITK | Q08881 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360796 | 0.96 | USP14 (0.37) | USP14POLBRXFP1MAPTITK | |
| Hydrochloric Acid SCHEMBL7350521 | 0.88 | POLB (0.37) | POLBRXFP1MAPTPDE2APDE3B | |
| SCHEMBL7354323 | 0.86 | USP14 (0.38) | USP14MAPT | |
| SCHEMBL7356649 | 0.85 | USP14 (0.37) | USP14MAPT | |
| SCHEMBL7359771 | 0.84 | PSMB5 (0.39) | USP14MAPT | |
| Hydrochloric Acid SCHEMBL7360554 | 0.84 | F2 (0.37) | — | |
| SCHEMBL7353094 | 0.82 | ELANE (0.35) | USP14POLBMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL7352796 | 0.80 | GAA (0.35) | USP14POLBMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL7356973 | 0.80 | USP14 (0.33) | USP14MAPT | |
| SCHEMBL7362376 | 0.79 | KMT2A (0.39) | USP14POLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |