Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | USP14 | P54578 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354323 | 0.90 | USP14 (0.38) | USP14MAPTTDP1CYP19A1MTNR1A | |
| SCHEMBL7356649 | 0.88 | USP14 (0.37) | PSMB5USP14MAPTTDP1CYP19A1 | |
| Hydrochloric Acid SCHEMBL7355413 | 0.86 | F2 (0.38) | — | |
| SCHEMBL7360796 | 0.86 | USP14 (0.37) | USP14MAPTTDP1CYP19A1FNTA | |
| SCHEMBL7353094 | 0.85 | ELANE (0.35) | PSMB5USP14MAPTTDP1CYP19A1 | |
| SCHEMBL7354501 | 0.84 | USP14 (0.39) | USP14MAPT | |
| SCHEMBL7352796 | 0.83 | GAA (0.35) | USP14MAPTTDP1TSHRSMN1; SMN2 | |
| SCHEMBL7356973 | 0.82 | USP14 (0.33) | PSMB5USP14MAPTTDP1CYP19A1 | |
| SCHEMBL7362376 | 0.82 | KMT2A (0.39) | USP14MAPTTDP1CYP19A1SMN1; SMN2 | |
| SCHEMBL7358416 | 0.80 | PLA2G4A (0.38) | CYP19A1MTNR1AMTNR1BLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |