Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP14 | P54578 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361404 | 0.87 | USP14 (0.34) | USP14CYP19A1MAPTTDP1 | |
| Iodide SCHEMBL7354314 | 0.87 | F2 (0.40) | SMN1; SMN2 | |
| SCHEMBL7353094 | 0.85 | ELANE (0.35) | KMT2AMEN1USP14ABCB1CYP19A1 | |
| SCHEMBL7356649 | 0.85 | USP14 (0.37) | USP14CYP19A1MAPTTDP1PLA2G4A | |
| SCHEMBL7354323 | 0.84 | USP14 (0.38) | USP14CYP19A1MAPTTDP1PLA2G4A | |
| SCHEMBL7352796 | 0.84 | GAA (0.35) | KMT2AMEN1SMN1; SMN2USP14ABCB1 | |
| SCHEMBL7359804 | 0.83 | SMN1; SMN2 (0.37) | KMT2AMEN1SMN1; SMN2CYP19A1POLB | |
| SCHEMBL7359771 | 0.82 | PSMB5 (0.39) | SMN1; SMN2USP14CYP19A1MAPTTDP1 | |
| SCHEMBL7360796 | 0.81 | USP14 (0.37) | USP14CYP19A1POLBMAPTTDP1 | |
| SCHEMBL7356973 | 0.81 | USP14 (0.33) | USP14CYP19A1MAPTTDP1PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |