Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP14 | P54578 | 3/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 9/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354323 | 0.90 | USP14 (0.38) | USP14PLA2G4AMAPTTDP1CYP19A1 | |
| SCHEMBL7359771 | 0.88 | PSMB5 (0.39) | USP14PLA2G4AMAPTTDP1CYP19A1 | |
| SCHEMBL7360796 | 0.87 | USP14 (0.37) | USP14MAPTTDP1CYP19A1FNTA | |
| SCHEMBL7359107 | 0.87 | F2 (0.39) | PLA2G4A | |
| SCHEMBL7353094 | 0.86 | ELANE (0.35) | USP14PLA2G4AMAPTTDP1CYP19A1 | |
| Hydrochloric Acid SCHEMBL7360989 | 0.86 | F2 (0.38) | PLA2G4A | |
| SCHEMBL7354501 | 0.85 | USP14 (0.39) | USP14MAPT | |
| SCHEMBL7362376 | 0.85 | KMT2A (0.39) | USP14PLA2G4AMAPTTDP1CYP19A1 | |
| SCHEMBL7352796 | 0.84 | GAA (0.35) | USP14MAPTTDP1 | |
| SCHEMBL7356973 | 0.83 | USP14 (0.33) | USP14PLA2G4AMAPTTDP1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |