Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | PNLIP | P16233 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8507827 | 0.92 | NPY5R (0.56) | NPY5RMMP8MME | |
| SCHEMBL8508382 | 0.88 | MMP8 (0.53) | NPY5RS1PR1MMP8FNTAFNTB | |
| SCHEMBL8509498 | 0.88 | MMP8 (0.55) | NPY5RMMP8FNTAFNTBMME | |
| SCHEMBL1374838 | 0.82 | NPY5R (0.58) | NPY5RS1PR1FNTAFNTBPPARG | |
| SCHEMBL1374841 | 0.82 | NPY5R (0.58) | NPY5RS1PR1FNTAFNTBPPARG | |
| SCHEMBL7355459 | 0.80 | MMP8 (0.60) | MMP8MME | |
| SCHEMBL7354557 | 0.80 | MMP8 (0.58) | NPY5RS1PR1MMP8 | |
| SCHEMBL8507870 | 0.80 | ANPEP (0.49) | NPY5RS1PR1FNTAFNTB | |
| SCHEMBL8508837 | 0.79 | FNTA (0.56) | NPY5RFNTAFNTBPNLIP | |
| SCHEMBL2610069 | 0.77 | KMT2A (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009736-A1 | MALONIC ACID BASED MATRIX METALLOPROTEINASE INHIBITORS | Roche Diagnostics GmbH (DE) | 2000-06-21 | — | — | EP | disclosed |
| EP-0911319-A1 | Malonic acid based matrix metalloproteinase inhibitors | Roche Diagnostics GmbH (DE) | 1999-04-28 | — | — | EP | disclosed |
| WO-1999011608-A1 | MALONIC ACID BASED MATRIX METALLOPROTEINASE INHIBITORS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-03-11 | — | — | WO | disclosed |