Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | HPGDS | O60760 | 6/20 | 0.53 |
| ▸ | FCER2 | P06734 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354848 | 1.00 | CAPN1 (0.55) | CAPN1CTSBHPGDSFCER2MMP1 | |
| SCHEMBL1498340 | 0.90 | MME (0.59) | — | |
| SCHEMBL1498341 | 0.90 | MME (0.59) | — | |
| SCHEMBL9109075 | 0.86 | HPGDS (0.56) | CAPN1CTSBHPGDSFCER2MMP1 | |
| SCHEMBL19584939 | 0.86 | MMP9 (0.56) | CAPN1CTSBHPGDSFCER2MMP1 | |
| SCHEMBL6853867 | 0.86 | HPGDS (0.56) | CAPN1CTSBHPGDSFCER2MMP1 | |
| SCHEMBL15810862 | 0.83 | CTSS (0.61) | HPGDSFCER2MMP1EPHX1PPARG | |
| SCHEMBL15743886 | 0.83 | HPGDS (0.53) | CAPN1CTSBHPGDSFCER2MMP1 | |
| SCHEMBL18403737 | 0.83 | HPGDS (0.53) | CAPN1CTSBHPGDSFCER2MMP1 | |
| SCHEMBL6248471 | 0.83 | CTSS (0.61) | HPGDSFCER2MMP1EPHX1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033576-A1 | CARBAMYL GUANIDINE AND AMIDINE PRODRUGS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-09-18 | — | — | WO | disclosed |
| US-5543425-A | ANTIAGGLOMERANTS | G. D. SEARLE & CO. (US) | 1996-08-06 | — | — | US | disclosed |
| EP-0513543-B1 | Derivatives of amidinophenylalanine, procedure for their preparation, their utilisation and anticoagulant compositions comprising them. | BEHRINGWERKE AG (DE) | 1995-10-25 | — | — | EP | disclosed |
| US-5409939-A | Phenyl amidine thio derivatives useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-04-25 | — | — | US | disclosed |
| WO-1994018162-A1 | PHENYL AMIDINE THIO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-18 | — | — | WO | disclosed |
| US-5264457-A | Phenyl amidines sulfonamides useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-11-23 | — | — | US | disclosed |
| WO-1993016038-A1 | PHENYL AMIDINES SULFONAMIDES USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-08-19 | — | — | WO | disclosed |
| EP-0513543-A1 | Derivatives of amidinophenylalanine, procedure for their preparation, their utilisation and anticoagulant compositions comprising them. | BEHRINGWERKE Aktiengesellschaft (DE) | 1992-11-19 | — | — | EP | disclosed |