SCHEMBL1498341

SCHEMBL1498341

N=C(N)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.59
NPSR1 Q6W5P4 1/20 0.58
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
NAALAD2 Q9Y3Q0 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.55
ACE P12821 2/20 0.54
CPA1 P15085 2/20 0.54
ACE2 Q9BYF1 2/20 0.54
CA2 P00918 2/20 0.54
CA1 P00915 1/20 0.54
FPR2 P25090 5/20 0.52
PTPN1 P18031 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1498340 1.00 MME (0.59) MMENPSR1MEN1KMT2ANAALAD2
SCHEMBL7354845 0.90 CAPN1 (0.55)
SCHEMBL7354848 0.90 CAPN1 (0.55)
Piperidine SCHEMBL1528563 0.87 L3MBTL1 (0.48) MMENPSR1MEN1KMT2ANAALAD2
SCHEMBL5964935 0.87 FOLH1 (0.58) MMENAALAD2ACECPA1ACE2
SCHEMBL6377128 0.87 FOLH1 (0.58) MMENAALAD2ACECPA1ACE2
SCHEMBL1012022 0.86 MME (0.63) MMENPSR1NAALAD2L3MBTL1ACE
SCHEMBL1012023 0.86 MME (0.63) MMENPSR1NAALAD2L3MBTL1ACE
SCHEMBL1012053 0.86 MME (0.63) MMENPSR1NAALAD2L3MBTL1ACE
SCHEMBL21791304 0.85 MME (0.58) MMENPSR1MEN1KMT2ANAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9255263-B2 Antithrombotic compounds KING'S COLLEGE LONDON (GB) 2016-02-09 US claimed
US-20120232014-A1 ANTITHROMBOTIC COMPOUNDS IMPERIAL INNOVATIONS LIMITED (GB) 2012-09-13 US claimed
EP-2473181-A1 ANTITHROMBOTIC COMPOUNDS King's College London (GB) 2012-07-11 EP claimed
WO-2011027175-A1 ANTITHROMBOTIC COMPOUNDS KING'S COLLEGE LONDON (GB) 2011-03-10 WO claimed
US-20100287636-A1 COMPOSITIONS AND METHODS FOR INHIBITING INDUCIBLE T CELL KINASE (ITK) AND TREATING ASTHMA AND BRONCHIAL INFLAMMATIONS San Diego State University Foundation, dba San Diego State University Research Foundation (US) 2010-11-11 US claimed
EP-1489968-B1 ASSAYS FOR CANCER PATIENT MONITORING BASED ON LEVELS OF ANALYTE COMPONENTS OF THE PLASMINOGEN ACTIVATOR SYSTEM IN BODY FLUID SAMPLES SIEMENS HEALTHCARE DIAGNOSTICS (US) 2009-02-18 EP claimed
WO-2008144351-A2 COMPOSITIONS AND METHODS FOR INHIBITING INDUCIBLE T CELL KINASE (ITK) AND TREATING ASTHMA AND BRONCHIAL INFLAMMATIONS SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2008-11-27 WO claimed
US-6287794-B1 Factor Vlla inhibitors AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-09-11 US claimed
WO-2001027138-A2 MODULATORS OF SREBP PROCESSING TULARIK INC. (US) 2001-04-19 WO claimed
JP-6025291-A None JP disclosed
JP-5155898-A None JP disclosed
CN-113811278-B Concealment of hypomineralized lesions 墨尔本大学 2024-12-31 CN disclosed
US-11981753-B2 Peptide compound and application thereof, and composition containing peptide compound SHANGPHARMA INNOVATION INC. (US) 2024-05-14 US disclosed
US-11807660-B2 Peptide compound and application thereof, and composition containing peptide compound XDCEXPLORER (SHANGHAI) CO., LTD. (CN) 2023-11-07 US disclosed
EP-0508220-A1 Derivatives of amindinophenylalanine, procedure for their preparation, their utilisation and compositions comprising them BEHRINGWERKE Aktiengesellschaft (DE) 1992-10-14 EP disclosed
WO-1992007869-A1 INHIBITORS AND SUBSTRATES OF THROMBIN THROMBOSIS RESEARCH INSTITUTE (GB) 1992-05-14 WO disclosed
US-4977168-A Derivatives of the N α-arylsulphonylaminoacyl-p-amidinophenyl-alaninamides, and their use as medicaments SANOFI (FR) 1990-12-11 US disclosed
EP-0236164-B1 DERIVATIVES OF N-ALPHA-ARYLSOLFONYLAMINOACYL P-AMIDINO-PHENYLALANINAMIDES, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND THEIR INTERMEDIATES SANOFI (FR) 1990-09-12 EP disclosed
US-4791102-A ANTICOAGULANTS SANOFI (FR) 1988-12-13 US disclosed
EP-0236164-A1 Derivatives of N-alpha-arylsolfonylaminoacyl p-amidino-phenylalaninamides, process for their preparation, their use as medicaments and their intermediates SANOFI (FR) 1987-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11981753-B2 Peptide compound and application thereof, and composition containing peptide compound KISS1R, NPY1R, GLP1R MME 289/4885NPSR1 65/4885MEN1 135/4885
US-11807660-B2 Peptide compound and application thereof, and composition containing peptide compound KISS1R, VIP, SSTR3 MME 245/4885NPSR1 71/4885MEN1 59/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.