Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361103 | 0.89 | TACR1 (0.44) | KMT2ARAB9AMEN1GAA | |
| SCHEMBL7355167 | 0.88 | KMT2A (0.46) | ALDH1A1KMT2AKDM4EHIF1AMAPT | |
| SCHEMBL7355177 | 0.87 | KMT2A (0.44) | ALDH1A1KMT2AKDM4EHIF1AMAPT | |
| SCHEMBL7357556 | 0.85 | OPRM1 (0.47) | KMT2ARAB9AMEN1GAA | |
| SCHEMBL7359741 | 0.84 | KMT2A (0.62) | ALDH1A1KMT2AMAPTMEN1CAPN1 | |
| SCHEMBL7364215 | 0.83 | RAB9A (0.51) | KMT2ARAB9AMEN1 | |
| SCHEMBL7354780 | 0.78 | LMNA (0.49) | ALDH1A1KMT2ATDP1RAB9AGAA | |
| SCHEMBL19289851 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KMT2AKDM4EHIF1ATDP1 | |
| SCHEMBL5879436 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KMT2AKDM4EHIF1AMAPT | |
| SCHEMBL5879498 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KMT2AKDM4EHIF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0753003-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995028416-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-26 | — | — | WO | disclosed |