Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.53 |
| ▸ | CTSD | P07339 | 7/20 | 0.47 |
| ▸ | CTSE | P14091 | 7/20 | 0.47 |
| ▸ | PGA5 | P0DJD9 | 6/20 | 0.47 |
| ▸ | PGC | P20142 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346803 | 0.83 | REN (0.64) | RENCTSDCTSEPGA5PGC | |
| SCHEMBL7385524 | 0.79 | MEN1 (0.61) | RENCTSDCTSEPGA5PGC | |
| SCHEMBL7317104 | 0.79 | MEN1 (0.61) | RENCTSDCTSEPGA5PGC | |
| SCHEMBL7331287 | 0.76 | REN (0.63) | RENCTSDCTSEPGA5PGC | |
| SCHEMBL7340387 | 0.76 | REN (0.53) | RENCTSDCTSEPGA5PGC | |
| SCHEMBL9680246 | 0.74 | REN (0.51) | RENCTSDCTSEPGA5PGC | |
| SCHEMBL7354503 | 0.73 | MEN1 (0.48) | RENCTSDCTSEPGA5PGC | |
| SCHEMBL9437597 | 0.70 | MEN1 (0.49) | RENCTSDCTSEPGA5 | |
| SCHEMBL9437603 | 0.69 | MEN1 (0.46) | RENCTSDCTSEPGA5PGC | |
| SCHEMBL7335450 | 0.69 | REN (0.58) | RENCTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258362-A | Enzyme inhibitors, amides with oxetane ring | ABBOTT LABORATORIES (US) | 1993-11-02 | — | — | US | disclosed |
| WO-1992022313-A1 | RENIN INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-12-23 | — | — | WO | disclosed |