Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.51 |
| ▸ | CTSD | P07339 | 2/20 | 0.48 |
| ▸ | PGA5 | P0DJD9 | 2/20 | 0.48 |
| ▸ | CTSE | P14091 | 2/20 | 0.48 |
| ▸ | PGC | P20142 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385524 | 0.80 | MEN1 (0.61) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7317104 | 0.80 | MEN1 (0.61) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7331287 | 0.77 | REN (0.63) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL26975364 | 0.76 | NLRP3 (0.52) | — | |
| SCHEMBL7346803 | 0.75 | REN (0.64) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL9680638 | 0.75 | NLRP3 (0.58) | — | |
| SCHEMBL7355315 | 0.74 | REN (0.53) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL9679311 | 0.74 | SOAT2 (0.59) | — | |
| SCHEMBL9679315 | 0.74 | SOAT2 (0.59) | — | |
| SCHEMBL7329310 | 0.74 | REN (0.48) | RENCTSDPGA5CTSEPGC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | claimed |
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |