Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.55 |
| ▸ | ITGAV | P06756 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sarcosine SCHEMBL7364548 | 0.93 | ITGB3 (0.50) | ITGB3ITGAVALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL16026979 | 0.89 | ITGB3 (0.59) | ITGB3ITGAVALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL16026981 | 0.89 | ITGB3 (0.59) | ITGB3ITGAVALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL8798480 | 0.86 | ITGB3 (0.54) | ITGB3ITGAVALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL6975926 | 0.86 | ALDH1A1 (0.57) | ITGB3ITGAVALDH1A1CYP2C19CYP1A2 | |
| Hydrochloric Acid SCHEMBL7943485 | 0.85 | ALDH1A1 (0.56) | ITGB3ITGAVALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL27522238 | 0.82 | ITGB3 (0.66) | ITGB3ITGAVALDH1A1CYP2C19CYP1A2 | |
| Arginine SCHEMBL7363181 | 0.81 | ITGB3 (0.43) | ITGB3ITGAVALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL6021271 | 0.79 | ALDH1A1 (0.49) | ITGB3ITGAVALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL7362007 | 0.77 | ALDH1A1 (0.63) | ALDH1A1CYP2C19CYP1A2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696231-A | ANTICOAGULANTS; CARDIOVASCULAR DISORDERS | CORVAS INTERNATIONAL, INC. (US) | 1997-12-09 | — | — | US | disclosed |
| EP-0801654-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES AS INHIBITORS OF FACTOR Xa | CORVAS INTERNATIONAL, INC. (US) | 1997-10-22 | — | — | EP | disclosed |
| WO-1996019493-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES AS INHIBITORS OF FACTOR Xa | CORVAS INTERNATIONAL, INC. (US) | 1996-06-27 | — | — | WO | disclosed |