Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.53 |
| ▸ | ITGAV | P06756 | 3/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 7/20 | 0.52 |
| ▸ | CA2 | P00918 | 7/20 | 0.52 |
| ▸ | CA5A | P35218 | 7/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7943485 | 0.99 | ALDH1A1 (0.56) | ALDH1A1CYP1A2CYP2C19ITGB3ITGAV | |
| SCHEMBL7355659 | 0.86 | ITGB3 (0.55) | ALDH1A1CYP1A2CYP2C19ITGB3ITGAV | |
| SCHEMBL16026979 | 0.86 | ITGB3 (0.59) | ALDH1A1CYP1A2CYP2C19ITGB3ITGAV | |
| SCHEMBL16026981 | 0.86 | ITGB3 (0.59) | ALDH1A1CYP1A2CYP2C19ITGB3ITGAV | |
| SCHEMBL27522238 | 0.85 | ITGB3 (0.66) | ALDH1A1CYP1A2CYP2C19ITGB3ITGAV | |
| SCHEMBL8798480 | 0.85 | ITGB3 (0.54) | ALDH1A1CYP1A2CYP2C19ITGB3ITGAV | |
| Sarcosine SCHEMBL7364548 | 0.80 | ITGB3 (0.50) | ALDH1A1CYP1A2CYP2C19ITGB3ITGAV | |
| SCHEMBL7413675 | 0.79 | ALDH1A1 (0.54) | ALDH1A1CYP1A2CYP2C19ITGB3ITGAV | |
| SCHEMBL14501722 | 0.79 | ITGB3 (0.72) | CYP1A2CYP2C19ITGB3ITGAVCA1 | |
| SCHEMBL5338029 | 0.79 | ITGB3 (0.72) | CYP1A2CYP2C19ITGB3ITGAVCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| EP-1098878-A1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | LABORATOIRE L. LAFON (FR) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000003986-A1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |