Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.62 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.43 |
| ▸ | MME | P08473 | 3/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350231 | 0.92 | PLA2G2A (0.68) | PLA2G2AITGB3ITGA2BPLA2G10 | |
| SCHEMBL7353690 | 0.83 | ITGB3 (0.43) | PLA2G2AITGB3ITGA2BMMELMNA | |
| SCHEMBL7355665 | 0.83 | ITGB3 (0.64) | PLA2G2AITGB3ITGA2BMMEPLA2G10 | |
| SCHEMBL7388743 | 0.82 | ITGB3 (0.55) | PLA2G2AITGB3ITGA2BMMELMNA | |
| SCHEMBL7389607 | 0.81 | ITGB3 (0.50) | PLA2G2AITGB3ITGA2BMMEMMEL1 | |
| SCHEMBL7381804 | 0.79 | ITGB3 (0.67) | PLA2G2AITGB3ITGA2BMMEMMEL1 | |
| SCHEMBL7378676 | 0.79 | ITGB3 (0.49) | PLA2G2AITGB3ITGA2BPLA2G10LMNA | |
| SCHEMBL7350097 | 0.79 | ITGB3 (0.46) | PLA2G2AITGB3ITGA2BMME | |
| SCHEMBL7357417 | 0.77 | ITGB3 (0.46) | PLA2G2AITGB3ITGA2BMME | |
| SCHEMBL7379875 | 0.77 | ITGB3 (0.65) | PLA2G2AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994018162-A1 | PHENYL AMIDINE THIO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-18 | — | — | WO | claimed |
| WO-1994018162-A1 | PHENYL AMIDINE THIO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-18 | — | — | WO | disclosed |