Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389607 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2BPLA2G2AS1PR2S1PR1 | |
| SCHEMBL7357417 | 0.86 | ITGB3 (0.46) | ITGB3ITGA2BPLA2G2AS1PR2S1PR1 | |
| SCHEMBL7378676 | 0.85 | ITGB3 (0.49) | ITGB3ITGA2BPLA2G2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7350495 | 0.84 | ITGB3 (0.45) | ITGB3ITGA2BPLA2G2AS1PR2S1PR1 | |
| SCHEMBL7381804 | 0.82 | ITGB3 (0.67) | ITGB3ITGA2BPLA2G2AMMECTSG | |
| SCHEMBL7379875 | 0.82 | ITGB3 (0.65) | ITGB3ITGA2BPLA2G2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7350092 | 0.82 | ITGB3 (0.69) | ITGB3ITGA2BPLA2G2A | |
| SCHEMBL7350231 | 0.81 | PLA2G2A (0.68) | ITGB3ITGA2BPLA2G2ASMN1; SMN2CTSG | |
| SCHEMBL7348662 | 0.81 | ITGB3 (0.50) | ITGB3ITGA2BPLA2G2ASMN1; SMN2CTSG | |
| SCHEMBL7386249 | 0.80 | ITGB3 (0.54) | ITGB3ITGA2BPLA2G2AALDH1A1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994018162-A1 | PHENYL AMIDINE THIO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-18 | — | — | WO | claimed |
| WO-1994018162-A1 | PHENYL AMIDINE THIO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-18 | — | — | WO | disclosed |