Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.38 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 3/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378676 | 0.89 | ITGB3 (0.49) | ITGB3ITGA2BPLA2G2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7381804 | 0.87 | ITGB3 (0.67) | ITGB3ITGA2BPLA2G2AMMEL1MME | |
| SCHEMBL9473562 | 0.87 | ENPP2 (0.42) | ITGB3ITGA2BPLA2G2ASMN1; SMN2S1PR2 | |
| SCHEMBL7350097 | 0.86 | ITGB3 (0.46) | ITGB3ITGA2BPLA2G2ASMN1; SMN2S1PR2 | |
| SCHEMBL7357417 | 0.86 | ITGB3 (0.46) | ITGB3ITGA2BPLA2G2ASMN1; SMN2S1PR2 | |
| SCHEMBL7379875 | 0.86 | ITGB3 (0.65) | ITGB3ITGA2BPLA2G2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7386249 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BPLA2G2AALDH1A1MMEL1 | |
| SCHEMBL7350495 | 0.85 | ITGB3 (0.45) | ITGB3ITGA2BPLA2G2ASMN1; SMN2S1PR2 | |
| SCHEMBL7348963 | 0.83 | ITGB3 (0.50) | ITGB3ITGA2BPLA2G2ASMN1; SMN2CTSG | |
| SCHEMBL7350231 | 0.83 | PLA2G2A (0.68) | ITGB3ITGA2BPLA2G2ASMN1; SMN2CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5220050-A | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-06-15 | — | — | US | claimed |
| WO-1992020705-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1992-11-26 | — | — | WO | claimed |
| US-5220050-A | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-06-15 | — | — | US | disclosed |
| WO-1992020705-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1992-11-26 | — | — | WO | disclosed |
| EP-0513810-A1 | Peptide mimetic compounds useful as platelet aggregation inhibitors | G.D. Searle & Co. (US) | 1992-11-19 | — | — | EP | disclosed |