Pratensein

Pratensein

SCHEMBL73557

COc1ccc(-c2coc3cc(O)cc(O)c3c2=O)cc1O

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.73
MAPT P10636 7/20 0.73
NPC1 O15118 6/20 0.73
KDM4E B2RXH2 5/20 0.73
MEN1 O00255 5/20 0.73
KMT2A Q03164 5/20 0.73
SMN1; SMN2 Q16637 5/20 0.73
TP53 P04637 5/20 0.73
ALDH1A1 P00352 4/20 0.73
HPGD P15428 4/20 0.73
MAPK1 P28482 4/20 0.73
HSD17B10 Q99714 4/20 0.73
CYP2C9 P11712 3/20 0.73
CYP2C19 P33261 3/20 0.73
CYP3A4 P08684 3/20 0.73
HSD17B2 P37059 3/20 0.73
NFKB1 P19838 3/20 0.73
NFKB2 Q00653 3/20 0.73
RELA Q04206 3/20 0.73
ALOX12 P18054 3/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pratensein SCHEMBL29349666 1.00 RAB9A (0.73) RAB9AMAPTNPC1KDM4EMEN1
Pratensein SCHEMBL29564983 1.00 RAB9A (0.73) RAB9AMAPTNPC1KDM4EMEN1
Pratensein SCHEMBL28502274 0.99 RAB9A (0.72) RAB9AMAPTNPC1KDM4EMEN1
SCHEMBL30380678 0.93 ABCB1 (0.76) RAB9AMAPTNPC1KDM4EMEN1
3'-O-Methylorobol SCHEMBL30380427 0.90 MAPT (0.73) RAB9AMAPTNPC1KDM4EMEN1
3'-O-Methylorobol SCHEMBL30380012 0.90 MAPT (0.73) RAB9AMAPTNPC1KDM4EMEN1
3'-O-Methylorobol SCHEMBL13730131 0.90 MAPT (0.73) RAB9AMAPTNPC1KDM4EMEN1
SCHEMBL11561656 0.87 MAPT (0.63) RAB9AMAPTNPC1KDM4EMEN1
SCHEMBL28740045 0.85 PTPN1 (0.70) RAB9AMAPTNPC1KDM4EMEN1
Biochanin SCHEMBL61258 0.85 RAB9A (1.00) RAB9AMAPTNPC1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025049883-A1 COMPOSITIONS AND METHODS FOR TREATING A DISEASE OR DISORDER ASSOCIATED WITH SENESCENCE JLM EXOGRADE, LLC (US) 2025-03-06 WO claimed
US-20240374554-A1 ISOFLAVONE DERIVATIVES MODULATING MUTANT BESTROPHIN 1 FOR TREATMENT OF BEST1-RELATED RETINOPATHIES UNIVERSITÄT REGENSBURG (DE) 2024-11-14 US claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
EP-4408415-A1 ISOFLAVONE DERIVATIVES MODULATING MUTANT BESTROPHIN 1 FOR TREATMENT OF BEST1-RELATED RETINOPATHIES Universität Regensburg (DE) 2024-08-07 EP claimed
US-20240042396-A1 Polymeric Membrane SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-02-08 US claimed
EP-4259316-A2 POLYMERIC MEMBRANE 3M Innovative Properties Company (US) 2023-10-18 EP claimed
WO-2023150072-A1 COMPOSITIONS AND METHODS FOR THE PRESERVATION OF PLANT MATTER SINCLAIR DAVID A (US) 2023-08-10 WO claimed
WO-2023052579-A1 ISOFLAVONE DERIVATIVES MODULATING MUTANT BESTROPHIN 1 FOR TREATMENT OF BEST1-RELATED RETINOPATHIES UNIVERSITÄT REGENSBURG (DE) 2023-04-06 WO claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
CN-115299346-A Method for improving alkaloid and flavone contents of subprostrate sophora tissue culture seedlings by using magnesium 广西壮族自治区药用植物园 2022-11-08 CN claimed
EP-1392239-A2 USE OF ISOFLAVONOIDS IN COSMETIC OR DERMATOLOGICAL PREPARATIONS FOR THE PROPHYLAXIS OR TREATMENT OF SENSITIVE SKIN Beiersdorf AG (DE) 2004-03-03 EP claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
US-20030147980-A1 Extraction of flavonoids MAABAROT PROJECT LAUNCHING AND MANAGEMENT LTD. (IL) 2003-08-07 US claimed
EP-1254131-A4 EXTRACTION OF FLAVONOIDS BIOREX HEALTH LTD (AU) 2003-04-23 EP claimed
CN-1395573-A Extraction of flavonoids BIOREX HEALTH LTD (AU) 2003-02-05 CN claimed
WO-2002087517-A2 USE OF ISOFLAVONOIDS IN COSMETIC OR DERMATOLOGICAL PREPARATIONS FOR THE PROPHYLAXIS OR TREATMENT OF SENSITIVE SKIN BEIERSDORF AG (DE) 2002-11-07 WO claimed
EP-1254131-A1 EXTRACTION OF FLAVONOIDS Biorex Health Limited (AU) 2002-11-06 EP claimed
US-20020107282-A1 Cosmetic composition containing an aminophenol derivative and an isoflavonoid L'OREAL (FR) 2002-08-08 US claimed
CN-1352935-A Cosmetics composition containing aminophenol derivatives and isoflavone like substance OREAL (FR) 2002-06-12 CN claimed
WO-2001051482-A1 EXTRACTION OF FLAVONOIDS BIOREX HEALTH LIMITED (AU) 2001-07-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107282-A1 Cosmetic composition containing an aminophenol derivative and an isoflavonoid TYR, CYP19A1, EYA3 RAB9A 3324/4885MAPT 3061/4885NPC1 4489/4885
US-20030147980-A1 Extraction of flavonoids ENGASE, GUSB, TYR RAB9A 1560/4885MAPT 2033/4885NPC1 685/4885
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB RAB9A 1281/4885MAPT 3926/4885NPC1 105/4885
US-20240374554-A1 ISOFLAVONE DERIVATIVES MODULATING MUTANT BESTROPHIN 1 FOR TREATMENT OF BEST1-RELATED RETINOPATHIES PEAK1, ING2, TEKT1 RAB9A 3261/4885MAPT 1810/4885NPC1 1232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.