Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389941 | 0.86 | S1PR1 (0.43) | GPR119PTPN2PTPN1PTPN6KDM4E | |
| SCHEMBL7484914 | 0.81 | GPR119 (0.42) | GPR119KDM4EPKMFAAHALDH1A1 | |
| SCHEMBL7385979 | 0.79 | GPR119 (0.42) | GPR119 | |
| SCHEMBL7394018 | 0.77 | GPR119 (0.41) | GPR119TGFBR1 | |
| SCHEMBL7391404 | 0.75 | GPR119 (0.41) | GPR119KDM4EPKMFAAHALDH1A1 | |
| SCHEMBL7358096 | 0.74 | HRH3 (0.41) | GPR119KDM4EPKMFAAHALDH1A1 | |
| SCHEMBL7481273 | 0.74 | GPR119 (0.41) | GPR119KDM4EPKMFAAHALDH1A1 | |
| SCHEMBL7394243 | 0.74 | GPR119 (0.41) | GPR119PTPN2PTPN1PTPN6KDM4E | |
| SCHEMBL7389887 | 0.72 | HRH3 (0.41) | GPR119PTPN2PTPN1PTPN6KDM4E | |
| SCHEMBL27403170 | 0.71 | GPR119 (0.46) | GPR119KDM4EPKMUSP30TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024405-A1 | IMIDAZOLIDIN-2-ONES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND METHOD OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1995-09-14 | — | — | WO | disclosed |