Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | CHKA | P35790 | 10/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10325407 | 0.83 | ACHE (0.64) | BCHEACHECHKALMNAALDH1A1 | |
| SCHEMBL7891723 | 0.82 | CHKA (0.52) | CHKALMNAALDH1A1HTTSMN1; SMN2 | |
| Bromide SCHEMBL2831425 | 0.80 | ACHE (0.68) | BCHEACHECHKALMNAALDH1A1 | |
| SCHEMBL93665 | 0.80 | CHKA (0.59) | BCHEACHECHKALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL11637202 | 0.80 | ACHE (0.61) | BCHEACHECHKALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL30164362 | 0.78 | CHKA (0.57) | BCHEACHECHKALMNAALDH1A1 | |
| SCHEMBL28628612 | 0.78 | CHKA (0.57) | BCHEACHECHKALMNAALDH1A1 | |
| Bromide SCHEMBL28611338 | 0.78 | CHKA (0.61) | BCHEACHECHKALMNAALDH1A1 | |
| Bromide SCHEMBL365151 | 0.78 | CHKA (0.61) | BCHEACHECHKALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL636283 | 0.78 | LMNA (0.63) | BCHEACHECHKALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907653-A1 | PROCESS FOR THE PREPARATION OF PENAM AND PENEM DERIVATIVES | ZENECA LIMITED (GB) | 1999-04-14 | — | — | EP | claimed |
| WO-1998000429-A1 | PROCESS FOR THE PREPARATION OF PENAM AND PENEM DERIVATIVES | ZENECA LIMITED (GB) | 1998-01-08 | — | — | WO | claimed |
| EP-0993448-A1 | (AMIDINO)6-MEMBERED AROMATICS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 2000-04-19 | — | — | EP | disclosed |
| EP-0991638-A1 | NOVEL GUANIDINE MIMICS AS FACTOR Xa INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2000-04-12 | — | — | EP | disclosed |
| EP-0907653-A1 | PROCESS FOR THE PREPARATION OF PENAM AND PENEM DERIVATIVES | ZENECA LIMITED (GB) | 1999-04-14 | — | — | EP | disclosed |
| WO-1998057934-A1 | (AMIDINO)6-MEMBERED AROMATICS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-23 | — | — | WO | disclosed |
| WO-1998057951-A1 | NOVEL GUANIDINE MIMICS AS FACTOR Xa INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-12-23 | — | — | WO | disclosed |
| WO-1998000429-A1 | PROCESS FOR THE PREPARATION OF PENAM AND PENEM DERIVATIVES | ZENECA LIMITED (GB) | 1998-01-08 | — | — | WO | disclosed |
| US-4503052-A | OXACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1985-03-05 | — | — | US | disclosed |