Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17627038 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL11947615 | 0.69 | ALDH1A1 (0.72) | NPSR1ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL4053266 | 0.68 | NPSR1 (0.42) | NPSR1ALDH1A1MAPTL3MBTL1GAA | |
| SCHEMBL4059489 | 0.67 | NPSR1 (0.41) | NPSR1ALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL15880689 | 0.67 | TSHR (0.42) | NPSR1ALDH1A1ADORA3ADORA2AADORA1 | |
| SCHEMBL10783107 | 0.65 | MAPK1 (0.41) | NPSR1ALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL22648680 | 0.64 | ADORA3 (0.39) | NPSR1ALDH1A1ADORA3ADORA2AADORA1 | |
| SCHEMBL1778197 | 0.64 | HSD17B10 (0.61) | NPSR1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL20816244 | 0.63 | L3MBTL1 (0.54) | NPSR1ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL4057468 | 0.63 | NPSR1 (0.36) | NPSR1ALDH1A1ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993009101-A1 | MERCAPTO-AMIDE DERIVATIVES AS INHIBITORS OF THE NEUTRAL ENDOPEPTIDASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-13 | — | — | WO | disclosed |