Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 3/20 | 0.37 |
| ▸ | USP14 | P54578 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TXK | P42681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352512 | 0.86 | ITK (0.37) | ITKUSP14PDK1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7362428 | 0.82 | NQO2 (0.41) | — | |
| Hydrochloric Acid SCHEMBL7357504 | 0.74 | F2 (0.46) | KDM4EALDH1A1MEN1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL7360735 | 0.74 | F2 (0.46) | — | |
| SCHEMBL7362376 | 0.74 | KMT2A (0.39) | USP14KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7361404 | 0.74 | USP14 (0.34) | USP14MAPTELANECACNA1H | |
| SCHEMBL6781674 | 0.73 | F2 (0.48) | ITKMAPTHTTHSD17B10 | |
| SCHEMBL7362439 | 0.72 | LMNA (0.38) | USP14KDM4EMAPTELANECACNA1H | |
| Hydrochloric Acid SCHEMBL7350504 | 0.72 | NQO2 (0.37) | KDM4EALDH1A1MEN1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL7352566 | 0.72 | F2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |