Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP14 | P54578 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.30 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362376 | 0.87 | KMT2A (0.39) | USP14CYP19A1MAPTTDP1 | |
| SCHEMBL7352796 | 0.85 | GAA (0.35) | USP14ELANEMAPTTDP1HTR3E | |
| SCHEMBL7353094 | 0.84 | ELANE (0.35) | USP14CYP19A1ELANEMAPTTDP1 | |
| SCHEMBL7359804 | 0.84 | SMN1; SMN2 (0.37) | CYP19A1MAPTHTR3EHTR3BHTR3A | |
| SCHEMBL7356973 | 0.81 | USP14 (0.33) | USP14CYP19A1ELANEMAPTTDP1 | |
| SCHEMBL7356649 | 0.81 | USP14 (0.37) | USP14CYP19A1MAPTTDP1CACNA1H | |
| SCHEMBL7354323 | 0.81 | USP14 (0.38) | USP14CYP19A1MAPTTDP1CACNA1H | |
| Hydrochloric Acid SCHEMBL7357014 | 0.80 | NQO2 (0.48) | — | |
| Hydrochloric Acid SCHEMBL7358291 | 0.79 | F2 (0.37) | — | |
| SCHEMBL7359771 | 0.79 | PSMB5 (0.39) | USP14CYP19A1MAPTTDP1CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |