Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.36 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.36 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359364 | 0.87 | BRD4 (0.46) | HRH3BRD4SMN1; SMN2 | |
| SCHEMBL7363075 | 0.85 | HRH3 (0.34) | HRH3BRD4 | |
| SCHEMBL7357679 | 0.83 | GLA (0.40) | ALDH1A1FKBP1AHRH3CYP2C19SMN1; SMN2 | |
| SCHEMBL7359680 | 0.83 | TSHR (0.36) | ALDH1A1POLBMAPT | |
| SCHEMBL8790973 | 0.81 | HRH3 (0.33) | ALDH1A1FKBP1AFKBP4FKBP5POLB | |
| SCHEMBL28640464 | 0.73 | ALDH1A1 (0.35) | ALDH1A1POLBHRH3PARP14KMT2A | |
| SCHEMBL22117724 | 0.73 | ALDH1A1 (0.35) | ALDH1A1POLBHRH3PARP14KMT2A | |
| SCHEMBL22117720 | 0.73 | ALDH1A1 (0.35) | ALDH1A1POLBHRH3PARP14KMT2A | |
| SCHEMBL22126915 | 0.71 | MEN1 (0.37) | ALDH1A1KMT2A | |
| SCHEMBL22126916 | 0.71 | MEN1 (0.37) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020172-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED β-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1996-07-04 | — | — | WO | disclosed |