Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 6/20 | 0.31 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363075 | 0.87 | HRH3 (0.34) | BRD4HRH3SSTR4SSTR1 | |
| SCHEMBL7356483 | 0.87 | ALDH1A1 (0.36) | BRD4HRH3SMN1; SMN2 | |
| SCHEMBL7359680 | 0.85 | TSHR (0.36) | — | |
| SCHEMBL8790645 | 0.81 | BRD4 (0.36) | BRD4LTA4HOPRD1HRH3SMN1; SMN2 | |
| SCHEMBL7357679 | 0.81 | GLA (0.40) | LTA4HHRH3SMN1; SMN2 | |
| SCHEMBL11079358 | 0.72 | TSHR (0.37) | HRH3 | |
| SCHEMBL8790494 | 0.72 | BRD4 (0.45) | BRD4SMN1; SMN2 | |
| SCHEMBL8790973 | 0.68 | HRH3 (0.33) | HRH3SMN1; SMN2 | |
| SCHEMBL2864044 | 0.68 | BRD4 (0.50) | BRD4LTA4HSMN1; SMN2 | |
| SCHEMBL22498216 | 0.68 | BRD4 (0.44) | BRD4LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020172-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED β-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1996-07-04 | — | — | WO | disclosed |