Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 8/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 5/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359364 | 0.87 | BRD4 (0.46) | HRH3BRD4SSTR4SSTR1 | |
| SCHEMBL7356483 | 0.85 | ALDH1A1 (0.36) | HRH3BRD4 | |
| SCHEMBL7359680 | 0.83 | TSHR (0.36) | — | |
| SCHEMBL8130203 | 0.70 | PLA2G10 (0.35) | KDM4EPKMBRD4KDM4DPLA2G10 | |
| SCHEMBL11079358 | 0.70 | TSHR (0.37) | HRH3 | |
| SCHEMBL26430857 | 0.70 | BRD4 (0.39) | BRD4PLA2G10PLA2G5DDB1CRBN | |
| SCHEMBL8790645 | 0.68 | BRD4 (0.36) | HRH3BRD4 | |
| SCHEMBL21285455 | 0.68 | NR1H2 (0.37) | BRD4 | |
| SCHEMBL23890605 | 0.68 | BRD4 (0.33) | BRD4PLA2G10PLA2G5DDB1CRBN | |
| SCHEMBL4573534 | 0.68 | KDM4D (0.37) | KDM4EPKMBRD4KDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020172-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED β-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1996-07-04 | — | — | WO | disclosed |