Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359045 | 0.91 | GRM1 (0.47) | GRM1KDM1AMAOAMAOBNAAA | |
| SCHEMBL7357694 | 0.90 | GRM1 (0.46) | GRM1KDM1AMAOAMAOBNAAA | |
| SCHEMBL576739 | 0.82 | L3MBTL1 (0.42) | MAOAMAOB | |
| SCHEMBL7359510 | 0.81 | GRM1 (0.47) | GRM1KDM1AMAOAMAOBNAAA | |
| SCHEMBL577037 | 0.77 | LMNA (0.41) | MAOAMAOB | |
| SCHEMBL576279 | 0.72 | L3MBTL1 (0.45) | MAOAMAOB | |
| SCHEMBL577428 | 0.70 | ALDH1A1 (0.37) | KDM1AMAOAMAOBNAAA | |
| SCHEMBL7664444 | 0.69 | GRM1 (0.64) | GRM1KDM1AMAOAMAOBCYP1A2 | |
| SCHEMBL7664441 | 0.69 | GRM1 (0.64) | GRM1KDM1AMAOAMAOBCYP1A2 | |
| SCHEMBL7763135 | 0.69 | CYP1A2 (0.50) | NAAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999036419-A1 | SUBSTITUTED LACTONES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-07-22 | — | — | WO | disclosed |