Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503134 | 1.00 | TP53 (0.31) | TP53 | |
| SCHEMBL5828102 | 0.76 | ALDH1A1 (0.36) | TP53 | |
| SCHEMBL6395056 | 0.67 | FOLH1 (0.34) | — | |
| SCHEMBL15799718 | 0.67 | LMNA (0.38) | — | |
| SCHEMBL7173837 | 0.66 | KDM4E (0.42) | — | |
| SCHEMBL5827487 | 0.66 | KDM4E (0.42) | — | |
| SCHEMBL10565313 | 0.64 | KDM4E (0.41) | — | |
| SCHEMBL503650 | 0.63 | ALDH1A1 (0.36) | — | |
| SCHEMBL22660988 | 0.63 | ALDH1A1 (0.36) | — | |
| SCHEMBL5515039 | 0.61 | HDAC4 (0.34) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955576-A | PEPTIDE ALDEHYDE ANALOGS THAT INHIBIT THROMBIN OR FACTOR XA; FOR PREVENTION OR TREATMENT OF ABNORMAL THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1999-09-21 | — | — | US | disclosed |
| EP-0684830-B1 | INHIBITORS OF THROMBOSIS | CORVAS INT INC (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5886146-A | N-ACYLATED OR SULFONATED TRIPEPTIDES FROM PROLINE, ARGININE AND AMINO ACID WITH CARBOXY OR TETRAZOLE GROUP | CORVAS INTERNATIONAL, INC. (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0627929-B1 | INHIBITORS OF THROMBOSIS | CORVAS INT INC (US) | 1998-09-30 | — | — | EP | disclosed |
| EP-0684830-A4 | INHIBITORS OF THROMBOSIS. | CORVAS INT INC (US) | 1996-04-17 | — | — | EP | disclosed |
| US-5492895-A | PEPTIDE ALDEHYDE ANALOGS | CORVAS INTERNATIONAL, INC. (US) | 1996-02-20 | — | — | US | disclosed |
| EP-0684830-A1 | INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1995-12-06 | — | — | EP | disclosed |
| EP-0627929-A4 | INHIBITORS OF THROMBOSIS. | CORVAS INT INC (US) | 1995-07-12 | — | — | EP | disclosed |
| EP-0627929-A1 | INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1994-12-14 | — | — | EP | disclosed |
| WO-1994017817-A1 | INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1994-08-18 | — | — | WO | disclosed |