Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360406 | 0.89 | F10 (0.48) | ALOX15NPC1RAB9A | |
| SCHEMBL7358443 | 0.87 | POLB (0.46) | CHRM1KDM4ETSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL7372751 | 0.83 | KCNMA1 (0.46) | KCNMA1CHRM1KDM4EGAAHPGD | |
| SCHEMBL7357718 | 0.82 | F10 (0.45) | CHRM1ALOX15TSHRFFAR2SMN1; SMN2 | |
| SCHEMBL5758058 | 0.78 | KCNMA1 (0.55) | KCNMA1CHRM1KDM4EGAAHPGD | |
| Hydrochloric Acid SCHEMBL7362651 | 0.76 | F10 (0.47) | — | |
| SCHEMBL7360970 | 0.75 | F10 (0.46) | KMT2AMEN1 | |
| SCHEMBL7381197 | 0.75 | KCNMA1 (0.52) | KCNMA1KDM4EGAAHPGDALOX15 | |
| SCHEMBL7359375 | 0.72 | F10 (0.44) | — | |
| SCHEMBL6106814 | 0.69 | F10 (0.48) | ALOX15ALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140881-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039111-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |