Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 13/20 | 0.42 |
| ▸ | MMP1 | P03956 | 7/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363695 | 0.90 | MME (0.46) | MMP3MMP1MMP2 | |
| SCHEMBL7357864 | 0.89 | MMP3 (0.43) | MMP3MMP1MMP2CTSL | |
| SCHEMBL7357685 | 0.87 | MMP3 (0.44) | MMP3MMP1MMP2OPRK1 | |
| SCHEMBL7361335 | 0.86 | MMP3 (0.42) | MMP3MMP1MMP2CTSL | |
| SCHEMBL7426285 | 0.86 | MMP3 (0.44) | MMP3MMP1MMP2 | |
| SCHEMBL7358575 | 0.84 | PTPN1 (0.46) | MMP3MMP1CTSL | |
| SCHEMBL7426196 | 0.84 | MMP3 (0.44) | MMP3MMP1MMP2CTSL | |
| SCHEMBL7358535 | 0.84 | MMP3 (0.41) | MMP3MMP1MMP2OPRK1 | |
| SCHEMBL7362029 | 0.83 | MME (0.41) | MMP3MMP1 | |
| SCHEMBL7423322 | 0.82 | ERAP2 (0.40) | MMP3MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |
| EP-0845002-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1998-06-03 | — | — | EP | disclosed |
| WO-1996040745-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1996-12-19 | — | — | WO | disclosed |