Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 9/20 | 0.44 |
| ▸ | MMP1 | P03956 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.41 |
| ▸ | IL1RN | P18510 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357864 | 0.91 | MMP3 (0.43) | MMP3MMP1PTPN1MMP2CTSL | |
| SCHEMBL7358575 | 0.88 | PTPN1 (0.46) | MMP3MMP1PTPN1ERAP2ERAP1 | |
| SCHEMBL7362029 | 0.88 | MME (0.41) | MMP3MMP1CTSK | |
| SCHEMBL7364809 | 0.87 | MMP3 (0.39) | MMP3MMP1MMP2CTSLCTSB | |
| SCHEMBL7357685 | 0.84 | MMP3 (0.44) | MMP3MMP1MMP2OPRD1 | |
| SCHEMBL7358708 | 0.84 | MMP3 (0.42) | MMP3MMP1MMP2CTSL | |
| SCHEMBL7361335 | 0.83 | MMP3 (0.42) | MMP3MMP1MMP2ERAP2CTSL | |
| SCHEMBL7363695 | 0.83 | MME (0.46) | MMP3MMP1MMP2 | |
| SCHEMBL7363969 | 0.82 | CTSK (0.47) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7426285 | 0.81 | MMP3 (0.44) | MMP3MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |