Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 14/20 | 0.44 |
| ▸ | MMP1 | P03956 | 7/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360708 | 0.90 | MMP3 (0.38) | MMP3MMP1SLC15A1MMP2ALDH1A1 | |
| SCHEMBL7357685 | 0.88 | MMP3 (0.44) | MMP3MMP1MMP2ALDH1A1MAPT | |
| SCHEMBL7361335 | 0.86 | MMP3 (0.42) | MMP3MMP1MMP2ALDH1A1MAPT | |
| SCHEMBL7358708 | 0.86 | MMP3 (0.42) | MMP3MMP1MMP2 | |
| SCHEMBL7358535 | 0.86 | MMP3 (0.41) | MMP3MMP1SLC15A1MMP2ALDH1A1 | |
| SCHEMBL7357864 | 0.85 | MMP3 (0.43) | MMP3MMP1MMP2 | |
| SCHEMBL7358850 | 0.85 | MMP3 (0.38) | MMP3MMP1MMP2ALPIPKM | |
| SCHEMBL7363695 | 0.83 | MME (0.46) | MMP3MMP1MMP2KMT2A | |
| SCHEMBL7423322 | 0.82 | ERAP2 (0.40) | MMP3MMP1MMP2MMP9 | |
| SCHEMBL7355861 | 0.82 | PSMB1 (0.41) | MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |