Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.59 |
| ▸ | CTSB | P07858 | 6/20 | 0.59 |
| ▸ | CTSK | P43235 | 3/20 | 0.57 |
| ▸ | CTSS | P25774 | 2/20 | 0.57 |
| ▸ | CTSH | P09668 | 2/20 | 0.57 |
| ▸ | CTSC | P53634 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4994648 | 0.81 | CTSB (0.61) | CTSLCTSBCTSKCTSSCTSH | |
| SCHEMBL4447641 | 0.80 | CTSB (0.52) | CTSLCTSBCTSKCTSSCTSH | |
| SCHEMBL7856906 | 0.76 | CTSB (0.78) | CTSLCTSBCTSKCTSSCTSH | |
| SCHEMBL9889135 | 0.76 | CTSB (0.82) | CTSLCTSBCTSKCTSSCTSH | |
| SCHEMBL7359034 | 0.76 | CTSB (0.82) | CTSLCTSBCTSKCTSSCTSH | |
| SCHEMBL4994654 | 0.72 | CTSB (0.79) | CTSLCTSBCTSKCTSSCTSH | |
| SCHEMBL14861102 | 0.72 | ALDH1A1 (0.51) | — | |
| SCHEMBL4318866 | 0.72 | CAPN1 (0.42) | — | |
| SCHEMBL8127874 | 0.72 | CTSB (0.62) | CTSLCTSBCTSKCTSSCTSH | |
| SCHEMBL9891652 | 0.71 | CTSL (0.73) | CTSLCTSBCTSKCTSSCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6287840-B1 | PEPTIDOMIMETICS; COUPLING, DEBLOCKING; ANTIARTHRITIC, ANTITUMOR, ANTICARCINOGENIC, AND ANTIMETASTASIS AGENTS; MUSCULAR DYSTROPHY, GLOMERULONEPHRITIS, MALARIA, ALZHEIMER*S DISEASE | AXYS PHARMACEUTICALS, INC. | 2001-09-11 | — | — | US | claimed |