Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR1F | P30939 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218524 | 0.83 | GABRA1 (0.52) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL9223733 | 0.82 | GABRA1 (0.51) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL7355774 | 0.81 | EGFR (0.60) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL9215592 | 0.78 | GABRA1 (0.49) | HTR6GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29643083 | 0.78 | GABRA1 (0.49) | HTR6GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28156121 | 0.77 | HTR6 (0.47) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL18795711 | 0.76 | SLC7A5 (0.49) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL30597932 | 0.76 | SLC7A5 (0.49) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL14602590 | 0.76 | ALDH1A1 (0.63) | HTR6GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28156846 | 0.74 | KDM4E (0.60) | HTR6HTR1ADRD2DRD4HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091945-A1 | CYCLIC CARBAMATES AND ISOXAZOLIDINES AS IIB/IIIA ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000481-A1 | CYCLIC CARBAMATES AND ISOXAZOLIDINES AS IIB/IIIA ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-01-06 | — | — | WO | disclosed |