Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14598314 | 0.96 | HTT (0.64) | HTTKEAP1NFE2L2ATMFOLH1 | |
| SCHEMBL7318682 | 0.96 | HTT (0.64) | HTTKEAP1NFE2L2ATMFOLH1 | |
| SCHEMBL14628582 | 0.96 | HTT (0.64) | HTTKEAP1NFE2L2ATMFOLH1 | |
| SCHEMBL7319378 | 0.95 | HTT (0.62) | HTTKEAP1NFE2L2FOLH1LMNA | |
| SCHEMBL8029846 | 0.95 | HTT (0.62) | HTTKEAP1NFE2L2FOLH1LMNA | |
| SCHEMBL7355388 | 0.92 | HTT (0.57) | HTTKEAP1NFE2L2FOLH1LMNA | |
| SCHEMBL989685 | 0.91 | TGM2 (0.55) | HTTKEAP1NFE2L2FOLH1LMNA | |
| SCHEMBL8039590 | 0.88 | HTT (0.52) | HTTKEAP1NFE2L2FOLH1LMNA | |
| SCHEMBL13622431 | 0.86 | HTT (0.50) | HTTKEAP1NFE2L2LMNASMN1; SMN2 | |
| SCHEMBL28645751 | 0.86 | HTT (0.50) | HTTKEAP1NFE2L2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999048911-A1 | MONOBACTAM ENZYME INHIBITORS | NAEJA PHARMACEUTICAL INC. (GB) | 1999-09-30 | — | — | WO | disclosed |
| EP-0646573-A1 | Preparation of protected and unprotected guanidino-substituted carboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-05 | — | — | EP | disclosed |