Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10682835 | 0.85 | ALOX15 (0.42) | HSD17B10NOS3NOS1NOS2ALOX15 | |
| SCHEMBL5216949 | 0.83 | ALDH1A1 (0.54) | HSD17B10NOS3NOS1NOS2ALOX15 | |
| SCHEMBL27323084 | 0.83 | ALDH1A1 (0.54) | HSD17B10NOS3NOS1NOS2ALOX15 | |
| SCHEMBL12967014 | 0.81 | ALOX15 (0.42) | HSD17B10ALOX15TDP1ALDH1A1CYP2C19 | |
| SCHEMBL12967039 | 0.81 | ALOX15 (0.42) | HSD17B10ALOX15TDP1ALDH1A1CYP2C19 | |
| SCHEMBL24633956 | 0.79 | NOS3 (0.58) | HSD17B10NOS3NOS1NOS2TDP1 | |
| SCHEMBL1287187 | 0.79 | NOS3 (0.58) | HSD17B10NOS3NOS1NOS2TDP1 | |
| SCHEMBL11413953 | 0.79 | NOS3 (0.58) | HSD17B10NOS3NOS1NOS2TDP1 | |
| SCHEMBL26763535 | 0.79 | HSD17B10 (0.46) | HSD17B10NOS3NOS1NOS2ALOX15 | |
| SCHEMBL14174568 | 0.78 | ALDH1A1 (0.47) | NOS3NOS1NOS2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014706-A1 | CYCLOPENTANE-DERIVED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS | PFIZER LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |