SCHEMBL5216949

SCHEMBL5216949

CCOC(=O)[C@@H](N)COC(C)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
LMNA P02545 1/20 0.54
HSD17B10 Q99714 1/20 0.54
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
NOS2 P35228 1/20 0.37
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SOAT1 P35610 1/20 0.36
HPGD P15428 1/20 0.35
CAD P27708 1/20 0.34
CPB2 Q96IY4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27323084 1.00 ALDH1A1 (0.54) ALDH1A1LMNAHSD17B10ALOX15TSHR
SCHEMBL10682835 0.84 ALOX15 (0.42) ALDH1A1LMNAHSD17B10ALOX15TSHR
SCHEMBL7359495 0.83 HSD17B10 (0.43) ALDH1A1LMNAHSD17B10ALOX15TSHR
SCHEMBL3868558 0.81 NOS3 (0.51) ALDH1A1LMNAHSD17B10ALOX15CYP2C19
SCHEMBL12967014 0.80 ALOX15 (0.42) ALDH1A1LMNAHSD17B10ALOX15TSHR
SCHEMBL13044359 0.80 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10ALOX15TSHR
SCHEMBL14682336 0.80 TDP1 (0.41) ALDH1A1LMNAHSD17B10TDP1NOS3
SCHEMBL13044370 0.80 TDP1 (0.41) ALDH1A1LMNAHSD17B10TDP1NOS3
SCHEMBL12967039 0.80 ALOX15 (0.42) ALDH1A1LMNAHSD17B10ALOX15TSHR
SCHEMBL419528 0.79 TDP1 (0.43) ALDH1A1LMNAHSD17B10TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017133517-A1 PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF 四川海思科制药有限公司 2017-08-10 WO disclosed
EP-1575900-A4 N-METHYL AMINO ACIDS UBIQUITOUS TECHNOLOGIES PTY LT (AU) 2007-02-21 EP disclosed
EP-1575900-A1 N-METHYL AMINO ACIDS UBIQUITOUS TECHNOLOGIES PTY LTD (AU) 2005-09-21 EP disclosed
WO-2004007427-A1 N-METHYL AMINO ACIDS UBIQUITOUS TECHNOLOGIES PTY LTD (AU) 2004-01-22 WO disclosed