Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364388 | 0.90 | SLC6A2 (0.56) | SLC6A2SLC6A4GLAFOLH1DPP7 | |
| SCHEMBL4749835 | 0.89 | FOLH1 (0.44) | SLC6A2SLC6A4GLAFOLH1DPP7 | |
| SCHEMBL17253753 | 0.85 | MAOB (0.47) | SLC6A2SLC6A4LOXL2EPHX1CYP19A1 | |
| SCHEMBL7359666 | 0.84 | LOXL2 (0.47) | LOXL2FFAR1 | |
| SCHEMBL7363755 | 0.83 | KCNJ1 (0.54) | SLC6A2SLC6A4GLAFOLH1LOXL2 | |
| SCHEMBL6331351 | 0.81 | SLC6A2 (0.49) | SLC6A2SLC6A4EPHX1 | |
| SCHEMBL17266185 | 0.81 | SLC6A2 (0.49) | SLC6A2SLC6A4EPHX1 | |
| SCHEMBL4496028 | 0.80 | GLA (0.57) | SLC6A2SLC6A4GLAFOLH1DPP7 | |
| SCHEMBL5262783 | 0.80 | GLA (0.57) | SLC6A2SLC6A4GLAFOLH1DPP7 | |
| SCHEMBL10606037 | 0.78 | FOLH1 (0.50) | SLC6A2SLC6A4GLAFOLH1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |