Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 15/20 | 0.45 |
| ▸ | CNR2 | P34972 | 10/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17266185 | 0.90 | SLC6A2 (0.49) | CNR1CNR2GRM4 | |
| SCHEMBL6331351 | 0.90 | SLC6A2 (0.49) | CNR1CNR2GRM4 | |
| SCHEMBL4749300 | 0.86 | LOXL2 (0.43) | LOXL2FFAR1 | |
| SCHEMBL7359657 | 0.84 | SLC6A2 (0.46) | LOXL2FFAR1 | |
| SCHEMBL7363757 | 0.83 | KCNJ1 (0.51) | LOXL2CNR1CNR2 | |
| SCHEMBL4748456 | 0.83 | CYP1A2 (0.51) | LOXL2 | |
| SCHEMBL7364388 | 0.81 | SLC6A2 (0.56) | CNR1GRM4 | |
| SCHEMBL29013128 | 0.80 | GRM4 (0.44) | LOXL2GRM4 | |
| SCHEMBL6420556 | 0.78 | S1PR1 (0.43) | CNR1CNR2FFAR1GRM4 | |
| SCHEMBL22395446 | 0.78 | GRM4 (0.49) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |