Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363757 | 0.87 | KCNJ1 (0.51) | KCNJ1KCNH2LOXL2VCAM1DPP4 | |
| SCHEMBL7364288 | 0.85 | KCNJ1 (0.56) | KCNJ1KCNH2GLAFOLH1LOXL2 | |
| SCHEMBL7359657 | 0.83 | SLC6A2 (0.46) | GLAFOLH1LOXL2DPP4DPP7 | |
| SCHEMBL7364388 | 0.81 | SLC6A2 (0.56) | GLAFOLH1DPP4DPP7FAP | |
| SCHEMBL4749835 | 0.80 | FOLH1 (0.44) | GLAFOLH1DPP4DPP7FAP | |
| SCHEMBL7364292 | 0.76 | KCNH2 (0.53) | KCNJ1KCNH2LOXL2VCAM1P4HB | |
| SCHEMBL6158758 | 0.72 | FOLH1 (0.48) | KCNJ1KCNH2GLAFOLH1DPP4 | |
| SCHEMBL17266185 | 0.72 | SLC6A2 (0.49) | SLC6A2SLC6A4EPHX1 | |
| SCHEMBL6331351 | 0.72 | SLC6A2 (0.49) | SLC6A2SLC6A4EPHX1 | |
| SCHEMBL7453828 | 0.72 | KCNJ1 (0.60) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |