Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359657 | 0.90 | SLC6A2 (0.46) | SLC6A2SLC6A4FOLH1GLADPP4 | |
| SCHEMBL6331351 | 0.90 | SLC6A2 (0.49) | SLC6A2SLC6A4CNR1TACR1MRGPRX1 | |
| SCHEMBL17266185 | 0.90 | SLC6A2 (0.49) | SLC6A2SLC6A4CNR1TACR1MRGPRX1 | |
| SCHEMBL4749835 | 0.86 | FOLH1 (0.44) | SLC6A2SLC6A4FOLH1GLADPP4 | |
| SCHEMBL17253753 | 0.81 | MAOB (0.47) | SLC6A2SLC6A4MAOAMAOBTSHR | |
| SCHEMBL18539225 | 0.81 | KDM1A (0.46) | SLC6A2SLC6A4GLADPP7TACR1 | |
| Hydrochloric Acid SCHEMBL3519614 | 0.81 | SLC6A2 (0.50) | SLC6A2SLC6A4FOLH1GLACNR1 | |
| SCHEMBL17463687 | 0.81 | SLC6A2 (0.44) | SLC6A2SLC6A4CNR1TACR1MRGPRX1 | |
| SCHEMBL7359666 | 0.81 | LOXL2 (0.47) | CNR1GRM4 | |
| SCHEMBL7363755 | 0.81 | KCNJ1 (0.54) | SLC6A2SLC6A4FOLH1GLADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |