Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 12/20 | 0.42 |
| ▸ | CNR2 | P34972 | 7/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363755 | 0.87 | KCNJ1 (0.54) | KCNJ1KCNH2LOXL2VCAM1DPP4 | |
| SCHEMBL7364292 | 0.85 | KCNH2 (0.53) | KCNJ1KCNH2LOXL2VCAM1P4HB | |
| SCHEMBL7359666 | 0.83 | LOXL2 (0.47) | LOXL2CNR1CNR2 | |
| SCHEMBL17266185 | 0.81 | SLC6A2 (0.49) | CNR1CNR2 | |
| SCHEMBL6331351 | 0.81 | SLC6A2 (0.49) | CNR1CNR2 | |
| SCHEMBL7364288 | 0.76 | KCNJ1 (0.56) | KCNJ1KCNH2LOXL2VCAM1FBP1 | |
| SCHEMBL7360304 | 0.75 | KCNJ1 (0.41) | KCNJ1KCNH2VCAM1FBP1P4HB | |
| SCHEMBL7364388 | 0.72 | SLC6A2 (0.56) | CNR1DPP4DPP7DPP8DPP9 | |
| SCHEMBL4749300 | 0.71 | LOXL2 (0.43) | LOXL2 | |
| SCHEMBL29013128 | 0.71 | GRM4 (0.44) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |