Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.45 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.45 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.45 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.45 |
| ▸ | FASN | P49327 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349744 | 0.92 | GRIK1 (0.45) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL7354860 | 0.86 | GRIK1 (0.47) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL7354439 | 0.84 | CYP1A2 (0.48) | MEN1POLBKMT2ANOX4 | |
| SCHEMBL7353587 | 0.82 | PGR (0.52) | PGRGRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL7352784 | 0.81 | PGR (0.49) | PGRGRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL9093246 | 0.79 | GRIA1 (0.58) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL7357010 | 0.78 | GRIK1 (0.47) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8609965 | 0.78 | CYP1A2 (0.57) | PGRGRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL7351187 | 0.76 | GRIK1 (0.55) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL9556876 | 0.75 | PGR (0.50) | PGRGRIK1GRIK2GRIK3GRIK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288065-B1 | CENTRAL NERVOUS SYSTEM DISORDERS; PARKINSON*S AND ALZHEIMER*S DISEASE | SCHERING AKTIENGESEELLSCHAFT (DE) | 2001-09-11 | — | — | US | disclosed |
| US-6057304-A | Quinoxaline-phosphonic acid derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |