Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.47 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.47 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354860 | 0.93 | GRIK1 (0.47) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL7947015 | 0.88 | CYP1A2 (0.48) | MEN1KMT2APOLBELANELMNA | |
| SCHEMBL7349744 | 0.86 | GRIK1 (0.45) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL7359747 | 0.78 | PGR (0.45) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL7353360 | 0.77 | GRIK1 (0.59) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL9395755 | 0.76 | PGR (0.54) | MEN1KMT2AALDH1A1GRIA1GRIA2 | |
| SCHEMBL8609548 | 0.76 | CYP1A2 (0.57) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL7474077 | 0.75 | SERPINE1 (0.51) | ELANESMN1; SMN2MAPTNOD2NOD1 | |
| SCHEMBL7349752 | 0.75 | ALDH1A1 (0.54) | MEN1KMT2APOLBELANELMNA | |
| SCHEMBL7352546 | 0.75 | PARG (0.47) | MEN1KMT2APOLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288065-B1 | CENTRAL NERVOUS SYSTEM DISORDERS; PARKINSON*S AND ALZHEIMER*S DISEASE | SCHERING AKTIENGESEELLSCHAFT (DE) | 2001-09-11 | — | — | US | disclosed |
| US-6057304-A | Quinoxaline-phosphonic acid derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |