Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HAT1 | O14929 | 2/20 | 0.32 |
| ▸ | EP300 | Q09472 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352796 | 0.88 | GAA (0.35) | SMN1; SMN2ALDH1A1MAPK1GAAL3MBTL1 | |
| SCHEMBL7361404 | 0.84 | USP14 (0.34) | MAPTCYP19A1HTR3EHTR3BHTR3A | |
| SCHEMBL7362376 | 0.83 | KMT2A (0.39) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL7358962 | 0.82 | F2 (0.46) | FFAR1FFAR4 | |
| SCHEMBL7353094 | 0.82 | ELANE (0.35) | ALDH1A1MAPK1L3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7357014 | 0.81 | NQO2 (0.48) | — | |
| SCHEMBL7356973 | 0.79 | USP14 (0.33) | MAPTCYP19A1HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL7361001 | 0.78 | F2 (0.44) | POLBFFAR1FFAR4 | |
| Iodide SCHEMBL7351241 | 0.77 | NQO2 (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7358416 | 0.77 | PLA2G4A (0.38) | HSD17B10ALDH1A1CYP19A1FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |