Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 2/20 | 0.56 |
| ▸ | CNR2 | P34972 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335030 | 0.86 | PGR (0.63) | PGRESR1LMNANR3C1ALDH1A1 | |
| SCHEMBL7326548 | 0.81 | NR3C1 (0.60) | PGRESR1LMNANR3C1ALDH1A1 | |
| SCHEMBL8549652 | 0.81 | ESR1 (0.66) | PGRESR1LMNANR3C1ALDH1A1 | |
| SCHEMBL7360039 | 0.80 | PGR (0.58) | PGRLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL5863377 | 0.79 | NR3C1 (0.71) | PGRESR1LMNANR3C1ALDH1A1 | |
| SCHEMBL6121815 | 0.78 | PGR (0.73) | PGRESR1LMNANR3C1ALDH1A1 | |
| SCHEMBL27593108 | 0.77 | ESR1 (1.00) | PGRESR1LMNANR3C1ALDH1A1 | |
| SCHEMBL5330652 | 0.74 | ESR1 (0.78) | PGRESR1LMNANR3C1ALDH1A1 | |
| SCHEMBL1279470 | 0.74 | PTGES (0.80) | PGRLMNANR3C1ALDH1A1NPSR1 | |
| SCHEMBL1279330 | 0.74 | TAS2R14 (0.74) | PGRLMNANR3C1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |