Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | ABCC9 | O60706 | 15/20 | 0.49 |
| ▸ | KCNJ11 | Q14654 | 15/20 | 0.49 |
| ▸ | ABCC8 | Q09428 | 8/20 | 0.49 |
| ▸ | KCNJ8 | Q15842 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347334 | 0.81 | P2RX7 (0.58) | NAMPTP2RX7ABCC9KCNJ11ABCC8 | |
| SCHEMBL7348943 | 0.80 | ABCC9 (0.54) | NAMPTP2RX7ABCC9KCNJ11ABCC8 | |
| SCHEMBL7349440 | 0.79 | ABCC9 (0.58) | NAMPTP2RX7ABCC9KCNJ11ABCC8 | |
| SCHEMBL8775157 | 0.76 | P2RX7 (0.41) | NAMPTP2RX7ABCC9KCNJ11ABCC8 | |
| SCHEMBL7360169 | 0.76 | P2RX7 (0.41) | NAMPTP2RX7ABCC9KCNJ11ABCC8 | |
| SCHEMBL9456841 | 0.73 | ABCC9 (0.73) | ABCC9KCNJ11ABCC8KCNJ8MEN1 | |
| SCHEMBL7347346 | 0.72 | ABCC9 (0.50) | P2RX7ABCC9KCNJ11ABCC8KCNJ8 | |
| SCHEMBL8919354 | 0.72 | ABCC9 (0.53) | NAMPTP2RX7ABCC9KCNJ11ABCC8 | |
| SCHEMBL7352529 | 0.70 | ABCC9 (0.48) | P2RX7ABCC9KCNJ11ABCC8KCNJ8 | |
| SCHEMBL8774811 | 0.70 | ABCC9 (0.69) | NAMPTP2RX7ABCC9KCNJ11ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655057-B1 | CYANOGUANIDINES AS POTASSIUM CHANNEL BLOCKERS | UPJOHN CO (US) | 1997-09-17 | — | — | EP | claimed |
| US-5567722-A | DIURETICS | THE UPJOHN COMPANY (US) | 1996-10-22 | — | — | US | claimed |
| EP-0655057-A1 | CYANOGUANIDINES AS POTASSIUM CHANNEL BLOCKERS. | UPJOHN CO (US) | 1995-05-31 | — | — | EP | claimed |
| WO-1994004499-A1 | CYANOGUANIDINES AS POTASSIUM CHANNEL BLOCKERS | THE UPJOHN COMPANY (US) | 1994-03-03 | — | — | WO | claimed |
| WO-1994004500-A1 | CYANOGUANIDINES AS POTASSIUM CHANNEL BLOCKERS | THE UPJOHN COMPANY (US) | 1994-03-03 | — | — | WO | claimed |
| EP-0655057-B1 | CYANOGUANIDINES AS POTASSIUM CHANNEL BLOCKERS | UPJOHN CO (US) | 1997-09-17 | — | — | EP | disclosed |
| US-5567722-A | DIURETICS | THE UPJOHN COMPANY (US) | 1996-10-22 | — | — | US | disclosed |
| EP-0655057-A1 | CYANOGUANIDINES AS POTASSIUM CHANNEL BLOCKERS. | UPJOHN CO (US) | 1995-05-31 | — | — | EP | disclosed |
| WO-1994004499-A1 | CYANOGUANIDINES AS POTASSIUM CHANNEL BLOCKERS | THE UPJOHN COMPANY (US) | 1994-03-03 | — | — | WO | disclosed |
| WO-1994004500-A1 | CYANOGUANIDINES AS POTASSIUM CHANNEL BLOCKERS | THE UPJOHN COMPANY (US) | 1994-03-03 | — | — | WO | disclosed |