SCHEMBL736035

SCHEMBL736035

COC(O)Nc1nc(N)nc(N)n1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
HTR7 P34969 2/20 0.30
ADRA1D P25100 1/20 0.30
ADRA1A P35348 1/20 0.30
ADRA1B P35368 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8603182 0.80 NPC1 (0.31)
SCHEMBL4371512 0.79 NPSR1 (0.51)
SCHEMBL9014254 0.79 MEN1 (0.34) LMNAHTR7ADRA1DADRA1AADRA1B
SCHEMBL5162098 0.78 HTR7 (0.31) HTR7ADRA1DADRA1AADRA1B
SCHEMBL14577069 0.77 HTR7 (0.33) HTR7ADRA1DADRA1AADRA1B
SCHEMBL8600401 0.76 MAPK1 (0.32) HTR7ADRA1DADRA1AADRA1B
SCHEMBL1011371 0.76 HTR7 (0.33) HTR7ADRA1DADRA1AADRA1B
SCHEMBL9197534 0.76 HTR7 (0.33) LMNAHTR7ADRA1DADRA1AADRA1B
SCHEMBL6723863 0.76 KMT2A (0.36) LMNAHTR7ADRA1DADRA1AADRA1B
SCHEMBL487591 0.75 LMNA (0.32) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8813803-B2 Pneumatic tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2014-08-26 US claimed
US-20130146197-A1 PNEUMATIC TIRE THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-06-13 US claimed
US-8137789-B2 Composition for matte layer formation, release sheet using the same, and synthetic leather produced using said release sheet DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-20 US claimed
US-20060137104-A1 Method of producing fabric ZHANG YU-GAO 2006-06-29 US claimed
EP-1492918-A4 METHOD OF PRODUCING FABRIC GUANGDONG ESQUEL KNITTERS CO L (CN) 2006-06-21 EP claimed
EP-1492918-A2 METHOD OF PRODUCING FABRIC Guangdong Esquel Kniiters Co., Ltd. (CN) 2005-01-05 EP claimed
WO-2003060222-A2 METHOD OF PRODUCING FABRIC GUANGDONG ESQUEL KNITTERS CO., LTD. (CN) 2003-07-24 WO claimed
US-20030135932-A1 Method of producing fabric GUANGDONG ESQUEL KNITTERS CO., LTD. (CN) 2003-07-24 US claimed
US-20030129538-A1 Method for eliminating corner round profile of the RELACS process MACRONIX INTERNATIONAL CO., LTD. 2003-07-10 US claimed
US-5858620-A Semiconductor device and method for manufacturing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1999-01-12 US claimed
EP-0357582-A2 Compositions comprising amino resins, epoxies and styrene allyl alcohol copolymers MONSANTO COMPANY (US) 1990-03-07 EP claimed
US-4808652-A ANTISOILANT COATING MONSANTO COMPANY (US) 1989-02-28 US claimed
US-4708984-A PROTECTIVE COATINGS AMERICAN CYANAMID COMPANY (US) 1987-11-24 US claimed
US-4517228-A COATING WITH PLASTIC AND TALC RELIANCE UNIVERSAL, INC. (US) 1985-05-14 US claimed
US-4320172-A Organopolysiloxane resin compositions for release papers SHIN-ETSU CHEMICAL CO., LTD. (JP) 1982-03-16 US claimed
JP-8302347-A None JP disclosed
JP-56104958-A None JP disclosed
US-4048136-A ACRYLIC RESINS, ENCAPSULATED METAL POWDERS, ALUMINUM MITSUI TOATSU KAGAKU KABUSHIKI KAISHA (MITSUI TOATSU CHEM., INC.) (JA) 1977-09-13 US disclosed
US-3985698-A Method for improving emulsion paint by adding an acrylic resin produced from a tertiary amine containing ethylenically unsaturated monomer KANSAI PAINT COMPANY, LTD. (JA) 1976-10-12 US disclosed
JP-H00228242-A 0001-01-01 JP disclosed