SCHEMBL9014254

SCHEMBL9014254

CCOC(O)Nc1nc(N)nc(N)n1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
KMT2A Q03164 1/20 0.34
HTR7 P34969 6/20 0.32
ADRA1D P25100 3/20 0.32
ADRA1A P35348 3/20 0.32
ADRA1B P35368 3/20 0.32
HTR2C P28335 1/20 0.31
HTR6 P50406 1/20 0.31
MAPT P10636 2/20 0.31
NPC1 O15118 1/20 0.31
JAK2 O60674 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9197534 0.86 HTR7 (0.33) HTR7ADRA1DADRA1AADRA1BHTR2C
SCHEMBL195696 0.83 HTR7 (0.34) CYP1A2HTR7ADRA1DADRA1AADRA1B
SCHEMBL1011371 0.82 HTR7 (0.33) HTR7ADRA1DADRA1AADRA1BHTR2C
SCHEMBL9112534 0.81 NPSR1 (0.51)
SCHEMBL9502375 0.81 MEN1 (0.36) MEN1CYP1A2KMT2AHTR7ADRA1D
SCHEMBL736035 0.79 LMNA (0.31) HTR7ADRA1DADRA1AADRA1BLMNA
SCHEMBL8130300 0.76 MEN1 (0.33) MEN1CYP1A2KMT2AHTR7ADRA1D
SCHEMBL15437996 0.75 MEN1 (0.33) MEN1CYP1A2KMT2AMAPTNPC1
SCHEMBL8201839 0.75 LMNA (0.31) HTR7ADRA1DADRA1AADRA1BHTR2C
Methoxymethane SCHEMBL27642128 0.74 NPC1 (0.31) MEN1CYP1A2KMT2AHTR7ADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0470280-B1 Method for manufacturing polymeric coated steel wires for rubber reinforcement TOKYO ROPE MFG CO (JP) 1996-12-11 EP disclosed
EP-0207621-B1 Functional polymers and their production NIPPON PAINT CO LTD (JP) 1995-04-05 EP disclosed
EP-0630921-A2 Functional polymers and their production NIPPON PAINT CO., LTD. (JP) 1994-12-28 EP disclosed
US-5354495-A Homo- or copolymerizable through ethylenic unsaturation NIPPON PAINT CO., LTD. (JP) 1994-10-11 US disclosed
US-5173341-A Coating wire with triazine-thiol derivative, drawing wire thorugh bath, polymerizing triazine-thiol TOKYO ROPE MFG. CO., LTD. (JP) 1992-12-22 US disclosed
EP-0177122-B1 ACRYLAMIDE DERIVATIVES Nippon Paint Co., Ltd. (JP) 1992-04-01 EP disclosed
EP-0470280-A1 Method for manufacturing polymeric coated steel wires for rubber reinforcement TOKYO ROPE MANUFACTURING CO., LTD. (JP) 1992-02-12 EP disclosed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US disclosed
EP-0207621-A2 Functional polymers and their production Nippon Paint Co., Ltd. (JP) 1987-01-07 EP disclosed
EP-0177122-A2 Acrylamide derivatives Nippon Paint Co., Ltd. (JP) 1986-04-09 EP disclosed